Toxicology and Applied Pharmacology: Vol. 228, Issue 1.

Regular Articles

2.
Assessment of the carcinogenic potential of mitemcinal (GM-611): Increased incidence of malignant lymphoma in a rat carcinogenicity study Pages 1-7 Etsuko Fujii, Kazuya Kimura, Keiji Mizoguchi, Atsuhiko Kato, Hisanori Takanashi, Zen Itoh, Satoshi Ōmura and Masami Suzuki


3.
Delta-9-tetrahydrocannabinol accumulation, metabolism and cell-type-specific adverse effects in aggregating brain cell cultures Pages 8-16 Florianne Monnet-Tschudi, Arno Hazekamp, Nicolas Perret, Marie-Gabrielle Zurich, Patrice Mangin, Christian Giroud and Paul Honegger


4.
Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity Pages 17-23 Jin Kyung Lee, Elaine M. Leslie, Maciej J. Zamek-Gliszczynski and Kim L.R. Brouwer


5.
Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes Pages 24-31 Byeong-Mo Kim and Hai-Won Chung


6.
Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase Pages 32-41 Dongren Yang, Angela Howard, Donald Bruun, Mispa Ajua-Alemanj, Cecile Pickart and Pamela J. Lein


7.
Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification Pages 42-48 Daniel K. Nomura, Kazutoshi Fujioka, Roger S. Issa, Anna M. Ward, Benjamin F. Cravatt and John E. Casida


8.
Phototoxicity and cytotoxicity of fullerol in human lens epithelial cells Pages 49-58 Joan E. Roberts, Albert R. Wielgus, William K. Boyes, Usha Andley and Colin F. Chignell


9.
Cytotoxic, genotoxic and cell-cycle disruptive effects of thio-dimethylarsinate in cultured human cells and the role of glutathione Pages 59-67 Takafumi Ochi, Kayoko Kita, Toshihide Suzuki, Alice Rumpler, Walter Goessler and Kevin A. Francesconi


10.
Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice Pages 68-75 Ping Cai, Rolf König, Paul J. Boor, Shakuntala Kondraganti, Bhupendra S. Kaphalia, M. Firoze Khan and G.A.S. Ansari


11.
Trans, trans-2,4-decadienal induced cell proliferation via p27 pathway in human bronchial epithelial cells Pages 76-83 Yun-Ching Chang and Pinpin Lin


12.
Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: Stimulation of interleukin-8 secretion, potentiation of interleukin-1β effect and increase in the transepithelial passage of commensal bacteria Pages 84-92 Marc Maresca, Nouara Yahi, Lama Younès-Sakr, Marilyn Boyron, Bertrand Caporiccio and Jacques Fantini


13.
The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses Pages 93-104 Donna E. Muscarella and Stephen E. Bloom


14.
Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation Pages 105-113 Gone-Jhe Wu, Ta-Liang Chen, Yune-Fang Ueng and Ruei-Ming Chen

Review

15.
Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures Pages 114-134 Wolfgang Dekant and Wolfgang Völkel


16.
Contents continued Page IBC


17.
Contents Page OBC