European Journal of Medicinal Chemistry: Vol 43, Issue 4

1.
Editorial board Page IFC


2.
Graphical contents list Pages iii-x

Original articles

3.
Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities Pages 675-682 Jong-Keun Son, Long-Xuan Zhao, Arjun Basnet, Pritam Thapa, Radha Karki, Younghwa Na, Yurngdong Jahng, Tae Cheon Jeong, Byeong-Seon Jeong, Chong-Soon Lee and Eung-Seok Lee


4.
Synthesis and in vitro antibacterial activities of novel oxazolidinones Pages 683-693 Brijesh Kumar Srivastava, Mukul R. Jain, Manish Solanki, Rina Soni, Darshan Valani, Sunil Gupta, Bhupendra Mishra, Vijay Takale, Prashant Kapadnis, Harilal Patel, Purvi Pandya, Jayendra Z. Patel and Pankaj R. Patel


5.
Synthesis, computational study and cytotoxic activity of new 4-hydroxycoumarin derivatives Pages 694-706 Stancho Stanchev, Georgi Momekov, Frank Jensen and Ilia Manolov


6.
Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones Pages 707-713 Z. Nowakowska, B. Kędzia and G. Schroeder


7.
QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES Pages 714-740 A.A. Toropov, A.P. Toropova and I. Raska Jr.


8.
Preparation and characterization of technetium and rhenium tricarbonyl complexes bearing the 4-nitrobenzyl moiety as potential bioreductive diagnostic radiopharmaceuticals. In vitro and in vivo studies Pages 741-748 Javier Giglio, Georgios Patsis, Ioannis Pirmettis, Minas Papadopoulos, Catherine Raptopoulou, Maria Pelecanou, Elsa León, Mercedes González, Hugo Cerecetto and Ana Rey


9.
Synthesis and anticonvulsant activity of some novel 3-aryl amino/amino-4-aryl-5-imino-Δ2-1,2,4-thiadiazoline Pages 749-754 Arun Gupta, Pradeep Mishra, Sushil K. Kashaw, Varsha Jatav and J.P. Stables


10.
Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives Pages 755-762 Fadoua Bouchikhi, Fabrice Anizon and Pascale Moreau


11.
Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives Pages 763-770 Gamal A. Elmegeed, Wagdy K.B. Khalil, Amira Abdel Raouf and Mervat M. Abdelhalim


12.
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors Pages 771-780 Sanjay Gupta, Lígia M. Rodrigues, Ana P. Esteves, Ana M.F. Oliveira-Campos, M. São José Nascimento, N. Nazareth, Honorina Cidade, Marta P. Neves, Eduarda Fernandes, Madalena Pinto, Nuno M.F.S.A. Cerqueira and Natércia Brás


13.
Towards predictive inhibitor design for the EGFR autophosphorylation activity Pages 781-791 Amor A. San Juan


14.
New amido derivatives as potential BKCa potassium channel activators. XI Pages 792-799 Vincenzo Calderone, Francesca Lidia Fiamingo, Gabriella Amato, Irene Giorgi, Oreste Livi, Alma Martelli and Enrica Martinotti


15.
Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity Pages 800-807 Christian Schlapper, Werner Seebacher, Marcel Kaiser, Reto Brun, Robert Saf and Robert Weis


16.
Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety Pages 808-815 Prakash Karegoudar, D. Jagdeesh Prasad, Mithun Ashok, Manjathuru Mahalinga, Boja Poojary and Bantwal Shivarama Holla


17.
Cyclic nucleotide phosphodiesterase type 4 inhibitors: Evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere Pages 816-829 Pierre Raboisson, Dominique Schultz, Christian Muller, Jean-Marie Reimund, Guillaume Pinna, Romain Mathieu, Philippe Bernard, Quoc-Tuan Do, Renee L. DesJarlais, Hélène Justiano, Claire Lugnier and Jean-Jacques Bourguignon


18.
Molecular modeling studies of phenoxypyrimidinyl imidazoles as p38 kinase inhibitors using QSAR and docking Pages 830-838 G.K. Ravindra, G. Achaiah and G.N. Sastry


19.
Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells Pages 839-845 Pal Perjési, Umashankar Das, Erik De Clercq, Jan Balzarini, Masame Kawase, Hiroshi Sakagami, James P. Stables, Tamas Lorand, Zsuzsanna Rozmer and Jonathan R. Dimmock


20.
Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines Pages 846-852 P. Mani Chandrika, T. Yakaiah, A. Raghu Ram Rao, B. Narsaiah, N. Chakra Reddy, V. Sridhar and J. Venkateshwara Rao


21.
Synthesis, properties and photodynamic inactivation of Escherichia coli by novel cationic fullerene C60 derivatives Pages 853-861 Mariana B. Spesia, M. Elisa Milanesio and Edgardo N. Durantini


22.
Schiff base transition metal complexes as novel inhibitors of xanthine oxidase Pages 862-871 Zhong-Lu You, Da-Hua Shi, Chen Xu, Qiang Zhang and Hai-Liang Zhu


23.
Antimycobacterial activity of diphenylpyraline derivatives Pages 872-879 Robert Weis, Johanna Faist, Ulrike di Vora, Klaus Schweiger, Barbara Brandner, Andreas J. Kungl and Werner Seebacher

Short communication

24.
In vitro PAI-1 inhibitory activity of oxalamide derivatives Pages 880-884 Mukul R. Jain, Shankar Shetty, Ganes Chakrabarti, Vrajesh Pandya, Ajay Sharma, Bhavesh Parmar, Soma Srivastava, Mehul Raviya, Hitesh Soni and Pankaj R. Patel

Preliminary communication

25.
Synthesis and anticancer activity of new class of bisphosphonates/phosphanamidates Pages 885-892 Y.B. Kiran, C. Devendranath Reddy, D. Gunasekar, C. Suresh Reddy, Annette Leon and Luiz C.A. Barbosa

Laboratory note

26.
An elegant synthesis of Zetaclausenamide Pages 893-896 Nianchun Ma, Kemei Wu and Liang Huang