28 Apr 2008

Biochemical Pharmacology: Vol 75, Issue 10

Commentary

2.
Uracil nucleotides: From metabolic intermediates to neuroprotection and neuroinflammation Pages 1869-1881 Davide Lecca and Stefania Ceruti

3.
The apelin–APJ system in heart failure: Pathophysiologic relevance and therapeutic potential Pages 1882-1892 Alan G. Japp and David E. Newby

4.
New players on the center stage: Sphingosine 1-phosphate and its receptors as drug targets Pages 1893-1900 Andrea Huwiler and Josef Pfeilschifter

Antibiotics and Chemotherapeutics

5.
Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: Characterization of a novel nucleobase transport activity Pages 1901-1911 Deepti Damaraju, Vijaya L. Damaraju, Miranda Brun, Delores Mowles, Michelle Kuzma, Richard C. Berendt, Michael B. Sawyer and Carol E. Cass

6.
Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines Pages 1912-1923 Adrián M. Ramos and Patricio Aller

7.
Fluoxetine mediates G0/G1 arrest by inducing functional inhibition of cyclin dependent kinase subunit (CKS)1 Pages 1924-1934 Anand Krishnan, Ramkumar Hariharan, S. Asha Nair and M. Radhakrishna Pillai

8.
Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: Role of reactive oxygen species production and glutathione depletion Pages 1935-1945 Conrad Ortiz, Laia Caja, Patricia Sancho, Esther Bertran and Isabel Fabregat

9.
Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway Pages 1946-1958 Young-Ho Kim, Dae-Hee Lee, Jae-Hoon Jeong, Zong Sheng Guo and Yong J. Lee

10.
Synthesis of bisphosphonate derivatives of ATP by T4 DNA ligase, ubiquitin activating enzyme (E1) and other ligases Pages 1959-1965 María A. Günther Sillero, Anabel de Diego, Francisco J. Pérez-Zúñiga and Antonio Sillero

Cardiovascular Pharmacology

11.
Diadenosine polyphosphates Ap3A and Ap4A, but not Ap5A or Ap6A, induce proliferation of vascular smooth muscle cells Pages 1966-1973 Peter Bobbert, Hartmut Schlüter, Heinz Peter Schultheiss and Hans Peter Reusch

Inflammation and Immunopharmacology

12.
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp Pages 1974-1980 Naoto Kamio, Hideki Hashizume, Sumi Nakao, Kiyoshi Matsushima and Hiroshi Sugiya

Metabolic Disorders and Endocrinology

13.
Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR Pages 1981-1993 Ying Cai, Qidi Wang, Zhidong Ling, Daniel Pipeleers, Paul McDermott, Mario Pende, Harry Heimberg and Mark Van de Casteele

Neuropharmacology

14.
Proteasome inhibitors prevent oxidative stress-induced nerve cell death by a novel mechanism Pages 1994-2006 Pamela Maher

15.
Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors Pages 2007-2019 Valérie Audinot, Anne Bonnaud, Line Grandcolas, Marianne Rodriguez, Nadine Nagel, Jean-Pierre Galizzi, Ales Balik, Sophie Messager, David G. Hazlerigg, Perry Barrett, Philippe Delagrange and Jean A. Boutin

Pharmacokinetics and Drug Metabolism

16.
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells Pages 2020-2033 Dae-Hee Lee, Clifford Kim, Lin Zhang and Yong J. Lee

Toxicology

17.
Benzo[a]pyrene inhibits osteoclastogenesis by affecting RANKL-induced activation of NF-κB Pages 2034-2044 I. Voronov, K. Li, H.C. Tenenbaum and M.F. Manolson

18.
Reactions of isodimethoate with human red cell acetylcholinesterase Pages 2045-2053 Peter Eyer, Maria Radtke and Franz Worek

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